Lipase Blood Test - Assess Pancreatic Health & Pancreatitis
Lipase is a digestive enzyme mainly produced by the pancreas. Its primary function is to break down dietary fats into free fatty acids and glycerol. In blood testing, lipase levels are most commonly used to assess pancreatic health, particularly when acute pancreatitis is suspected. Lipase is considered more sensitive and specific than amylase for detecting pancreatic inflammation.
Why Test Lipase?
A lipase test is crucial when investigating acute abdominal pain, particularly if symptoms like nausea, vomiting, loss of appetite, or upper abdominal discomfort are present. It is the preferred marker for detecting pancreatic inflammation and is also used to monitor chronic pancreatitis and other gastrointestinal conditions that affect fat digestion.
What Do High Lipase Levels Mean?
Elevated lipase levels usually signal inflammation of the pancreas — most commonly acute pancreatitis. Other possible causes include chronic pancreatitis, gallstones, pancreatic duct blockage, kidney failure, coeliac disease, peptic ulcer perforation, or certain cancers. Because lipase is cleared by the kidneys, impaired kidney function can also raise levels.
What Do Low Lipase Levels Mean?
Low lipase levels are less common and often not clinically concerning. However, they may indicate reduced pancreatic enzyme production, which can occur in advanced chronic pancreatitis, cystic fibrosis, or other conditions that impair fat digestion. Reference range is typically 0.3-1.0 ukat/L.
Symptoms to Watch For
- Severe upper abdominal pain radiating to the back
- Nausea and vomiting
- Loss of appetite
- Abdominal tenderness and bloating
- Fatty or greasy stools
Who Should Get Tested?
- People with acute abdominal pain, especially in the upper abdomen
- Patients with suspected or known pancreatitis
- Individuals with gallstone-related symptoms
- Those with chronic digestive issues involving fat malabsorption
How to Prepare for Your Test
No special preparation is typically required. Your doctor may advise fasting if the test is part of a broader panel. Bring valid ID to the sampling clinic.
Order Your Blood Test
Test your Lipase levels with an accredited Swedish laboratory. Results within days, reviewed by Wellth.
Frequently Asked Questions
Is lipase more accurate than amylase for pancreatitis?
Can kidney problems affect lipase levels?
What is the normal range for lipase?
Can gallstones cause high lipase?
Reviewed by
Wellth Team
Wellth
Our content is written and reviewed by Wellth, and fact-checked against peer-reviewed research and current Swedish clinical guidelines.
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The information on this page is provided for informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. Wellth provides health information and testing services but is not a substitute for clinical care. Always consult a qualified healthcare provider if you have questions about a medical condition. If you are experiencing severe or urgent symptoms, contact your doctor or call 1177 Vårdguiden. Blood test results should be interpreted by a qualified healthcare professional in the context of your complete medical history.