Neutrophils – Your Body's First Line of Immune Defense

Neutrophils are a type of white blood cell (granulocyte) that accounts for 40–75% of all leukocytes. They are produced in the bone marrow and are the first cells to arrive at the site of infection, where they engulf and destroy bacteria and fungi. A neutrophil count is a key part of the differential white blood cell count.

Why Test Neutrophils?

Testing neutrophils helps evaluate immune defense, detect infections, investigate inflammation, and monitor bone marrow function. It is particularly important during chemotherapy or immunosuppressive treatment, when neutropenia increases the risk of serious infections.

What Do High Neutrophils Levels Mean?

Elevated neutrophils (neutrophilia) may indicate bacterial infection, acute inflammation, physical or emotional stress, smoking, cortisone therapy, or blood disorders like leukemia.

What Do Low Neutrophils Levels Mean?

Low neutrophils (neutropenia) suggest a weakened immune system. Causes may include viral infections, bone marrow disorders, autoimmune diseases, B12 or folate deficiency, or chemotherapy.

Symptoms to Watch For

  • Recurrent infections
  • Fever without a clear cause
  • Fatigue and weakness
  • Mouth ulcers
  • Slow wound healing
  • Bruising easily

Who Should Get Tested?

  • People with recurrent or severe infections
  • Patients undergoing cancer treatment
  • Those with unexplained fever or fatigue
  • Anyone with suspected blood or bone marrow disease
  • Individuals monitoring immunosuppressive therapy

How to Prepare for Your Test

No special preparation is needed. Bring valid ID to your appointment.

Frequently Asked Questions

What is a normal neutrophil count?
The normal range is typically 1.5–7.5 × 10⁹/L. Values below 1.5 indicate neutropenia; values below 0.5 indicate severe neutropenia.
Can an infection cause both high and low neutrophils?
Yes. Bacterial infections usually raise neutrophils, while some viral infections (like influenza or HIV) can lower them by suppressing bone marrow production.
Is neutropenia dangerous?
It can be. Severe neutropenia significantly increases the risk of bacterial and fungal infections. If you have very low neutrophils and develop a fever, seek medical attention immediately.
NW

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Wellth

Our content is written and reviewed by Wellth, and fact-checked against peer-reviewed research and current Swedish clinical guidelines.

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Medical Disclaimer

The information on this page is provided for informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. Wellth provides health information and testing services but is not a substitute for clinical care. Always consult a qualified healthcare provider if you have questions about a medical condition. If you are experiencing severe or urgent symptoms, contact your doctor or call 1177 Vårdguiden. Blood test results should be interpreted by a qualified healthcare professional in the context of your complete medical history.