Quiz
2
Order
3
Lab
4
Results
5
Report
6
Plan

Kidney & Electrolytes

Ionised Calcium (Free)

Kidney & Electrolytes

Ionised Calcium (Free)

Ionized calcium is the biologically active fraction of calcium that directly influences muscle contractions, nerve signalling, and bone health.

135 SEK

VAT-exempt medical service

  • Results in 5 working days
  • 116 sampling locations
  • No doctor's referral needed
  • Sample: Blood (venous)
  • Laboratory: Synlab
Find a sampling location →

What does this test measure?

Unlike total calcium, which includes both protein-bound and free forms, ionized calcium measures only the portion that is freely available to the body. This makes it the more clinically relevant marker in many situations, particularly when parathyroid disorders, vitamin D deficiency, kidney disease, or critical illness is involved. Because ionized calcium is not influenced by albumin levels, it provides a truer picture of calcium status.

This test is recommended when evaluating suspected parathyroid gland disorders, vitamin D deficiency, malabsorption syndromes, or kidney conditions such as uraemia. It is also the preferred measurement in hospitalised or critically ill patients, where albumin levels may be abnormal and total calcium is harder to interpret.

What a high value can mean

Elevated ionized calcium (hypercalcaemia) may point to hyperparathyroidism, certain cancers, excess vitamin D, or other endocrine disorders. It can cause symptoms such as excessive thirst, frequent urination, nausea, bone pain, and confusion.

What a low value can mean

Low ionized calcium (hypocalcaemia) may suggest hypoparathyroidism, vitamin D deficiency, kidney disease, magnesium deficiency, or malabsorption. Symptoms include muscle cramps, numbness, tingling, and in severe cases, cardiac arrhythmias.

Read more about this marker →

Associated symptoms

  • Muscle spasms or cramps
  • Numbness and tingling around the mouth or in the fingers
  • Fatigue or mood changes
  • Bone pain (high levels)
  • Heart palpitations

Who should consider this test

  • People with suspected parathyroid disorders
  • Those being evaluated for vitamin D deficiency
  • Patients with chronic kidney disease
  • Individuals with malabsorption conditions
  • Hospitalised patients where total calcium is unreliable

Before your appointment

No fasting required. Special sample handling may be necessary -- follow any instructions from the laboratory. Bring valid ID.

  • Bring photo ID to the sampling location.
  • You do not need a doctor's referral — your referral is issued when you order.
  • Tell the staff which test you have ordered if they ask.

How it works

  1. 1

    Order your test

    Choose your test and pay online. Your lab referral is created straight away.

  2. 2

    Give your sample

    Visit any of our partner sampling locations. No appointment needed at most of them.

  3. 3

    The lab analyses it

    Your sample is analysed at an accredited Swedish laboratory.

  4. 4

    Get your results

    Your values appear in your account with reference ranges and an explanation of each marker.

Good to know

How is ionized calcium different from total calcium?

Total calcium includes both protein-bound and free forms. Ionized calcium measures only the free, active form, which is more clinically relevant because it directly affects bodily functions.

Why might my doctor order ionized calcium instead of total?

If your albumin is low, total calcium may appear falsely low. Ionized calcium gives a more accurate reading in these situations, as well as in critically ill patients.

Can blood pH affect ionized calcium?

Yes. Changes in blood pH alter the binding of calcium to albumin. Acidosis increases ionized calcium, while alkalosis decreases it.