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Paracetamol Analysis
Other
This test measures paracetamol (acetaminophen) levels in the blood to assess whether the drug poses a risk to the liver.
VAT-exempt medical service
Paracetamol (also known as acetaminophen) is one of the most widely used over-the-counter medications for reducing pain and fever. While safe at recommended doses, paracetamol can become toxic to the liver when taken in excess or over prolonged periods. In the liver, paracetamol is metabolised into a reactive byproduct called NAPQI, which can damage liver cells if not adequately neutralised by the body's glutathione stores.
This test is essential when an overdose is suspected or when there are concerns about liver strain during long-term use. It helps quickly determine whether blood levels of paracetamol are within a safe range. The test is particularly important for people with underlying liver disease, regular alcohol use, or those taking other medications that affect liver function.
What a high value can mean
High levels (typically above 300 nmol/L) may indicate toxic exposure and require urgent medical evaluation. This could result from intentional or accidental overdose, or from impaired liver function that reduces the body's ability to clear the drug. Even moderately elevated levels can harm the liver, especially with additional risk factors. Prompt treatment with acetylcysteine is often needed to prevent damage.
What a low value can mean
Normal values (typically below 33 nmol/L) suggest no immediate risk from the drug. However, in acute overdose situations, a low value may not rule out toxicity if the test is done many hours after ingestion. In chronic use, blood levels may remain within reference but still contribute to liver strain, so follow-up liver function tests (ALT, AST, PK-INR) may be necessary.
No special preparation is needed. In suspected overdose situations, the timing of the test relative to ingestion is critical for interpretation. Bring valid ID to the sampling clinic.
Order your test
Choose your test and pay online. Your lab referral is created straight away.
Give your sample
Visit any of our partner sampling locations. No appointment needed at most of them.
The lab analyses it
Your sample is analysed at an accredited Swedish laboratory.
Get your results
Your values appear in your account with reference ranges and an explanation of each marker.
Toxicity depends on the dose and individual factors. Liver damage can begin within hours of a large overdose. The critical treatment window is typically within 8 hours of ingestion, when acetylcysteine is most effective.
For healthy adults, the maximum recommended dose is typically 4 grams (4000 mg) per day. People with liver disease or regular alcohol use should take less. Always follow the dosing instructions on the packaging.
Yes. If the test is performed many hours after ingestion, paracetamol may have already been metabolised while liver damage is still progressing. Liver function tests (ALT, AST) provide a more complete picture.