Immune & Inflammation
Serum IgG
Immune & Inflammation
Main antibody in blood. Reflects long-term immune response and past infections.
VAT-exempt medical service
IgG makes up around three quarters of the antibodies in blood. After an infection or vaccination, IgG maintains protection against that specific microbe. A total IgG test does not show what you are immune to; it shows how much antibody you produce overall, which is what matters when immune deficiency is suspected.
The test is used when recurrent or unusually severe infections suggest an immune deficiency, particularly repeated pneumonia or sinus infections, and to follow known deficiency. It is also used when conditions causing protein loss, or treatments that suppress the immune system, may have lowered antibody levels.
What a high value can mean
A raised total IgG is seen with chronic infection, liver disease, and chronic inflammatory or autoimmune conditions. A markedly raised value produced by a single cell line can indicate a blood disorder such as myeloma, and is investigated with additional tests including protein electrophoresis.
What a low value can mean
A low IgG means reduced antibody production and a greater susceptibility to bacterial infection. Causes include primary immune deficiency, treatment with corticosteroids, immunosuppressants or rituximab, loss of protein through the kidneys or gut, and blood disorders. A low result with recurrent infections should be assessed by a doctor, as treatment with immunoglobulin replacement exists.
No special preparation is needed. Bring valid ID to your appointment.
Order your test
Choose your test and pay online. Your lab referral is created straight away.
Give your sample
Visit any of our partner sampling locations. No appointment needed at most of them.
The lab analyses it
Your sample is analysed at an accredited Swedish laboratory.
Get your results
Your values appear in your account with reference ranges and an explanation of each marker.
IgG is the main antibody in blood and carries long-term immunity. IgA protects the mucous membranes of the gut and airways. IgE is involved in allergic reactions and in the response to parasites.
Yes. If the cause is a medicine or protein loss, treating that may be enough. In primary immune deficiency with recurrent infections, regular immunoglobulin replacement is given under specialist care.