Hormones

DHEAS (Dehydroepiandrosterone Sulphate)

DHEAS is made in the adrenal cortex and converted in the tissues into testosterone and oestrogen. Because almost all of it comes from the adrenal glands, the test helps establish whether increased androgen effect originates there or in the ovaries. Levels peak in the twenties and then decline gradually with age, which is normal.

Why Test DHEAS?

The test is relevant for increased hair growth, acne, hair loss and irregular periods, as part of an assessment of raised androgens. It is also used when disease of the adrenal glands is suspected. DHEAS is interpreted alongside testosterone and SHBG.

What Do High DHEAS Levels Mean?

A moderately raised DHEAS is often seen in PCOS. Markedly raised values can indicate an adrenal tumour or congenital adrenal hyperplasia and should be investigated further. Signs of excess androgen include acne, oily skin, increased facial and body hair, hair loss at the crown and irregular periods.

What Do Low DHEAS Levels Mean?

DHEAS falls naturally with age, so low values in older people are expected. Markedly low values can be seen in adrenal insufficiency and in disease of the pituitary, particularly alongside fatigue, low blood pressure and weight loss.

Symptoms to Watch For

  • Acne and oily skin
  • Increased facial or body hair
  • Hair loss at the crown
  • Irregular or absent periods
  • Fatigue and lack of energy (low value)

Who Should Get Tested?

  • People being investigated for PCOS or increased hair growth
  • People with acne or hair loss alongside irregular periods
  • People being investigated for disease of the adrenal glands

How to Prepare for Your Test

No fasting is required. DHEAS varies little across the day and can be taken at any point in the menstrual cycle. Bring valid ID to your appointment.

Order Your Blood Test

Test your DHEAS levels with an accredited Swedish laboratory. Results within days, reviewed by Wellth.

DHEAS (Dehydroepiandrosterone Sulfate) →

Frequently Asked Questions

What is the difference between DHEA and DHEAS?
DHEAS is the sulphated form. It circulates at higher concentration and is steadier across the day, which makes it more reliable to measure in blood.
Does DHEAS change with age?
Yes. It peaks in the twenties and then declines steadily, which is why reference intervals are given by age.
Can DHEAS show whether I have PCOS?
Not on its own. DHEAS is often moderately raised in PCOS, but the diagnosis is made from the pattern of periods, signs of excess androgen and ultrasound, assessed by a doctor.
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Our content is written and reviewed by Wellth, and fact-checked against peer-reviewed research and current Swedish clinical guidelines.

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Medical Disclaimer

The information on this page is provided for informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. Wellth provides health information and testing services but is not a substitute for clinical care. Always consult a qualified healthcare provider if you have questions about a medical condition. If you are experiencing severe or urgent symptoms, contact your doctor or call 1177 Vårdguiden. Blood test results should be interpreted by a qualified healthcare professional in the context of your complete medical history.