Hormones
DHEAS (Dehydroepiandrosterone Sulfate)
Hormones
Adrenal hormone precursor. Indicator of adrenal function and androgen production.
VAT-exempt medical service
DHEAS is made in the adrenal cortex and converted in the tissues into testosterone and oestrogen. Because almost all of it comes from the adrenal glands, the test helps establish whether increased androgen effect originates there or in the ovaries. Levels peak in the twenties and then decline gradually with age, which is normal.
The test is relevant for increased hair growth, acne, hair loss and irregular periods, as part of an assessment of raised androgens. It is also used when disease of the adrenal glands is suspected. DHEAS is interpreted alongside testosterone and SHBG.
What a high value can mean
A moderately raised DHEAS is often seen in PCOS. Markedly raised values can indicate an adrenal tumour or congenital adrenal hyperplasia and should be investigated further. Signs of excess androgen include acne, oily skin, increased facial and body hair, hair loss at the crown and irregular periods.
What a low value can mean
DHEAS falls naturally with age, so low values in older people are expected. Markedly low values can be seen in adrenal insufficiency and in disease of the pituitary, particularly alongside fatigue, low blood pressure and weight loss.
No fasting is required. DHEAS varies little across the day and can be taken at any point in the menstrual cycle. Bring valid ID to your appointment.
Order your test
Choose your test and pay online. Your lab referral is created straight away.
Give your sample
Visit any of our partner sampling locations. No appointment needed at most of them.
The lab analyses it
Your sample is analysed at an accredited Swedish laboratory.
Get your results
Your values appear in your account with reference ranges and an explanation of each marker.
DHEAS is the sulphated form. It circulates at higher concentration and is steadier across the day, which makes it more reliable to measure in blood.
Yes. It peaks in the twenties and then declines steadily, which is why reference intervals are given by age.
Not on its own. DHEAS is often moderately raised in PCOS, but the diagnosis is made from the pattern of periods, signs of excess androgen and ultrasound, assessed by a doctor.