Other
Angiotensin-Converting Enzyme (ACE)
Other
S-ACE measures angiotensin-converting enzyme in the blood, a key marker for sarcoidosis and other inflammatory granulomatous conditions.
VAT-exempt medical service
Angiotensin-converting enzyme (ACE) is an enzyme involved in regulating blood pressure and fluid balance. When certain inflammatory conditions cause the body to form granulomas — small clusters of immune cells — ACE levels in the blood often rise. The S-ACE test captures this change, making it a valuable tool for investigating diseases like sarcoidosis, which most commonly affects the lungs but can also involve the skin, eyes, and other organs.
An ACE test is most often ordered when sarcoidosis is suspected, particularly if you have a persistent cough, fatigue, shortness of breath, swollen lymph nodes, or unusual findings on a chest X-ray. It can also aid in diagnosing or monitoring other granulomatous diseases such as tuberculosis, and in investigating unexplained high blood pressure or kidney problems. Tracking ACE levels over time helps assess disease activity and treatment response.
What a high value can mean
Elevated ACE levels may indicate active sarcoidosis or another granulomatous condition. Less commonly, high values can stem from lung or kidney inflammation or other rare diseases. A high result is a diagnostic clue but not conclusive on its own — additional tests are typically required to confirm a diagnosis.
What a low value can mean
A normal or low ACE level is common and generally not a concern. Low values can occur if you are taking ACE inhibitors, a common medication for high blood pressure. In rare cases, reduced enzyme production related to kidney disease or other conditions may also lower ACE levels.
Remember to bring valid ID to the sampling clinic.
Order your test
Choose your test and pay online. Your lab referral is created straight away.
Give your sample
Visit any of our partner sampling locations. No appointment needed at most of them.
The lab analyses it
Your sample is analysed at an accredited Swedish laboratory.
Get your results
Your values appear in your account with reference ranges and an explanation of each marker.
Sarcoidosis is an inflammatory disease in which the body forms small clusters of immune cells called granulomas, most often in the lungs and lymph nodes, but also in the skin, eyes, and other organs.
Yes. Other granulomatous conditions such as tuberculosis, as well as certain kidney or lung disorders, can raise ACE levels. The result must always be interpreted alongside other clinical findings.
Yes, ACE inhibitor medications lower ACE levels in the blood and may produce a falsely low result. Inform your healthcare provider about all medications you are taking.